Polymers in linear shear flow: a numerical study

We study the dynamics of a single polymer subject to thermal fluctuations in a linear shear flow. The polymer is modeled as a finitely extendable nonlinear elastic FENE dumbbell. Both orientation and elongation dynamics are investigated numerically as a function of the shear strength, by means of a new efficient integration algorithm. The results are in agreement with recent experiments.Comment: 7 pages, see also the preceding paper (http://arxiv.org/nlin.CD/0503028

Evaluación del confort térmico urbano por medio de la temperatura fisiológica equivalente (PET), en la ciudad de Mendoza

La climatología urbana se ha dedicado a estudiar los balances de energía de la ciudad a fin de establecer las relaciones de temperatura y humedad en su entorno. Debido a la fuerte interacción entre el hombre y el ambiente construido, la ciudad puede modificar el balance térmico establecido. El presente trabajo estudia el confort biometeorológico bajo diversas condiciones constructivas y de verde urbano de la ciudad de Mendoza. Para lo cual se han recopilado datos de dos años de mediciones simultáneas entre diferentes puntos. Uno de los indicadores bioclimáticos actualmente más usado es el PET (Physiological Equivalent Temperature). Se presenta el uso de PET el cual muestra diferencias de hasta 15ºC entre zonas bajo la corona de especies arbóreas y zonas hormigonadas. Se concluye en la necesidad de seleccionar y preservar especies arbóreas debido a su rol en la disminución de la radiación directa y consecuentemente mejora del confort.Urban climatology has been devoted to study the energy balances of the city to establish the relationship of temperature and humidity in their environment. Due to the strong interaction between man and the built environment the city can change the established heat balance. This paper studies the biometeorological comfort in the city of Mendoza under various constructive conditions and urban green spaces. These conditions were analyzed using meteorological data of simultaneous measurements between different points for a two years period. One of the most widely used bioclimatic indicators is currently the Physiological Equivalent Temperature (PET). We report the use of PET which shows differences up to 15 °C between areas under the crown of tree species and paved areas. The conclusion reinforces the need to select and preserve urban tree species due to its role in reducing the direct radiation and in improving the urban thermal comfort.Asociación Argentina de Energías Renovables y Medio Ambiente (ASADES

Evaluación del confort térmico urbano por medio de la temperatura fisiológica equivalente (PET), en la ciudad de Mendoza

La climatología urbana se ha dedicado a estudiar los balances de energía de la ciudad a fin de establecer las relaciones de temperatura y humedad en su entorno. Debido a la fuerte interacción entre el hombre y el ambiente construido, la ciudad puede modificar el balance térmico establecido. El presente trabajo estudia el confort biometeorológico bajo diversas condiciones constructivas y de verde urbano de la ciudad de Mendoza. Para lo cual se han recopilado datos de dos años de mediciones simultáneas entre diferentes puntos. Uno de los indicadores bioclimáticos actualmente más usado es el PET (Physiological Equivalent Temperature). Se presenta el uso de PET el cual muestra diferencias de hasta 15ºC entre zonas bajo la corona de especies arbóreas y zonas hormigonadas. Se concluye en la necesidad de seleccionar y preservar especies arbóreas debido a su rol en la disminución de la radiación directa y consecuentemente mejora del confort.Urban climatology has been devoted to study the energy balances of the city to establish the relationship of temperature and humidity in their environment. Due to the strong interaction between man and the built environment the city can change the established heat balance. This paper studies the biometeorological comfort in the city of Mendoza under various constructive conditions and urban green spaces. These conditions were analyzed using meteorological data of simultaneous measurements between different points for a two years period. One of the most widely used bioclimatic indicators is currently the Physiological Equivalent Temperature (PET). We report the use of PET which shows differences up to 15 °C between areas under the crown of tree species and paved areas. The conclusion reinforces the need to select and preserve urban tree species due to its role in reducing the direct radiation and in improving the urban thermal comfort.Asociación Argentina de Energías Renovables y Medio Ambiente (ASADES

Evaluación del confort térmico urbano por medio de la temperatura fisiológica equivalente (PET), en la ciudad de Mendoza

La climatología urbana se ha dedicado a estudiar los balances de energía de la ciudad a fin de establecer las relaciones de temperatura y humedad en su entorno. Debido a la fuerte interacción entre el hombre y el ambiente construido, la ciudad puede modificar el balance térmico establecido. El presente trabajo estudia el confort biometeorológico bajo diversas condiciones constructivas y de verde urbano de la ciudad de Mendoza. Para lo cual se han recopilado datos de dos años de mediciones simultáneas entre diferentes puntos. Uno de los indicadores bioclimáticos actualmente más usado es el PET (Physiological Equivalent Temperature). Se presenta el uso de PET el cual muestra diferencias de hasta 15ºC entre zonas bajo la corona de especies arbóreas y zonas hormigonadas. Se concluye en la necesidad de seleccionar y preservar especies arbóreas debido a su rol en la disminución de la radiación directa y consecuentemente mejora del confort.Urban climatology has been devoted to study the energy balances of the city to establish the relationship of temperature and humidity in their environment. Due to the strong interaction between man and the built environment the city can change the established heat balance. This paper studies the biometeorological comfort in the city of Mendoza under various constructive conditions and urban green spaces. These conditions were analyzed using meteorological data of simultaneous measurements between different points for a two years period. One of the most widely used bioclimatic indicators is currently the Physiological Equivalent Temperature (PET). We report the use of PET which shows differences up to 15 °C between areas under the crown of tree species and paved areas. The conclusion reinforces the need to select and preserve urban tree species due to its role in reducing the direct radiation and in improving the urban thermal comfort.Asociación Argentina de Energías Renovables y Medio Ambiente (ASADES

Therapeutic sequences in patients with grade 1−2 neuroendocrine tumors (NET): an observational multicenter study from the ELIOS group

Purpose: Many different treatments are suggested by guidelines to treat grade 1−2 (G1−G2) neuroendocrine tumors (NET). However, a precise therapeutic algorithm has not yet been established. This study aims at identifying and comparing the main therapeutic sequences in G1−G2 NET. Methods: A retrospective observational Italian multicenter study was designed to collect data on therapeutic sequences in NET. Median progression-free survival (PFS) was compared between therapeutic sequences, as well as the number and grade of side effects and the rate of dose reduction/treatment discontinuation. Results: Among 1182 patients with neuroendocrine neoplasia included in the ELIOS database, 131 G1–G2 gastroenteropancreatic, lung and unknown primary NET, unresectable or persistent/relapsing after surgery, treated with ≥2 systemic treatments, were included. Four main therapeutic sequences were identified in 99 patients: (A) somatostatin analogs (SSA) standard dose to SSA high dose (n = 36), (B) SSA to everolimus (n = 31), (C) SSA to chemotherapy (n = 17), (D) SSA to peptide receptor radionuclide therapy (PRRT) (n = 15). Median PFS of the second-line treatment was not reached in sequence A, 33 months in sequence B, 20 months in sequence C, 30 months in sequence D (p = 0.16). Both total number and severity of side effects were significantly higher in sequences B and C than A and D (p = 0.04), as well as the rate of dose reduction/discontinuation (p = 0.03). Conclusions: SSA followed by SSA high dose, everolimus, chemotherapy or PRRT represent the main therapeutic sequences in G1−G2 NET. Median PFS was not significantly different between sequences. However, the sequences with SSA high dose or PRRT seem to be better tolerated than sequences with everolimus or chemotherapy

Joint Power Control and Structural Health Monitoring in Industry 4.0 Scenarios using Eclipse Arrowhead and Web of Things

The integration of legacy IoT ecosystems in Industry 4.0 scenarios requires human effort to adapt single devices. This process would highly benefit from features like device lookup, loose coupling and late binding. In this paper, we tackle the issue of integrating legacy monitoring systems and actuation systems in an industrial scenario, by looking into the Web of Things (WoT) as a communication standard and the Eclipse Arrowhead Framework (AHF) as a service orchestrator. More specifically, we propose a general architectural approach to enable closed-loop automation between the above mentioned legacy systems by leveraging the adaptation of the WoT to the AHF. Then, we develop a rule-based engine that enables the control of the actuation based on sensor values. Finally, we present a proof-of-concept use case where we integrate a Structural Health Monitoring (SHM) scenario with a power control actuation subsystem using the developed component

牛糞堆肥を施用した畑地における大腸菌の流出抑制に関する研究

2013東京農業大

Building a smart city service platform in Messina with the #SmartME project

© 2018 IEEE. Some words mark an era, and "Smart City" is definitely one of these. A Smart City is an urban area where the Information and Communication Technologies (ICT) are employed to improve citizens' Quality of Life (QoL) in areas such as: mobility, urban surveillance, and energy management. Throughout this paper, we present the #SmartME project, which aims to create an infrastructure and an ecosystem of "smart" services by exploiting existing devices, sensors, and actuators distributed in the city of Messina. We also present the Stack4Things framework, which is the management core of the #SmartME project

Intergenerational and intrafamilial phenotypic variability in 22q11.2 deletion syndrome subjects

BACKGROUND: 22q11.2 deletion syndrome (22q11.2DS) is a common microdeletion syndrome, which occurs in approximately 1:4000 births. Familial autosomal dominant recurrence of the syndrome is detected in about 8-28% of the cases. Aim of this study is to evaluate the intergenerational and intrafamilial phenotypic variability in a cohort of familial cases carrying a 22q11.2 deletion. METHODS: Thirty-two 22q11.2DS subjects among 26 families were enrolled. RESULTS: Second generation subjects showed a significantly higher number of features than their transmitting parents (212 vs 129, P = 0.0015). Congenital heart defect, calcium-phosphorus metabolism abnormalities, developmental and speech delay were more represented in the second generation (P < 0.05). Ocular disorders were more frequent in the parent group. No significant difference was observed for the other clinical variables. Intrafamilial phenotypic heterogeneity was identified in the pedigrees. In 23/32 families, a higher number of features were found in individuals from the second generation and a more severe phenotype was observed in almost all of them, indicating the worsening of the phenotype over generations. Both genetic and epigenetic mechanisms may be involved in the phenotypic variability. CONCLUSIONS: Second generation subjects showed a more complex phenotype in comparison to those from the first generation. Both ascertainment bias related to patient selection or to the low rate of reproductive fitness of adults with a more severe phenotype, and several not well defined molecular mechanism, could explain intergenerational and intrafamilial phenotypic variability in this syndrome

Inventario de emisiones a la atmósfera de compuestos orgánicos persistentes seleccionados en Mendoza para el año 2011

El presente trabajo trata la identificación y análisis de fuentes específicas de Contaminantes Orgánicos Persistentes junto con el cálculo de sus emisiones, en el área del Gran Mendoza, durante el año 2011. Se estimaron las emisiones de Bifenilos Policlorados (PCB), Hexaclorobenceno (HCB), y Diclorodifeniltricloroetano (DDT). Debido a la gran variedad de fuentes y compuestos involucrados y a limitaciones en la disponibilidad de información, no se utilizó un método armonizado para todos los compuestos en la preparación del inventario. Los datos presentados en este estudio proporcionan un panorama general de las emisiones en el Gran Mendoza. Finalmente, se destaca la necesidad de un esfuerzo mayor en la caracterización y validación de las emisiones, tanto para la obtención de relaciones entre fuentes y receptores, como también para el desarrollo de estrategias de control. Asimismo, esta información es crucial para lograr una reducción en la carga de estas sustancias, a nivel local y regional.The present work is focused on the identification and analysis of specific sources of Permanent Organic Pollutants together with the calculation of emissions in the Great Mendoza during 2011. Emissions of polychlorinated biphenyls (PCBs), hexachlorobenzene (HCB) and Dichloro-diphenyl-trichloroethane (DDT) were estimated. Due to the wide variety of sources and compounds involved and the limited availability of information, a harmonized method for all compounds in the preparation of the inventory was not used. Data submitted in this study provide an overview of the emissions in the Great Mendoza urban area. Finally, great efforts in the characterization and validation of emissions, both for obtaining relationships between sources and sinks, as well as for the development of strategies to control them are needed. Also, this information is crucial to achieve a reduction in the burden of these substances, at local and regional level.Asociación Argentina de Energías Renovables y Medio Ambiente (ASADES